When it comes to innovation in Asia, one country stands head and shoulders above the rest, and that is Singapore. The city-state consistently ranks among the top 10 innovative countries in global surveys.

In the Global Innovation Index for 2014, a joint project by Cornell University in New York, [Hong Kong Company Formation & Registration]INSEAD and the World Intellectual Property Organization, Singapore ranks seventh out of 143 countries.

Solidiance, a Singapore-based corporate advisory group, recently ranked Singapore as the leading city in Asia Pacific for innovation.

With strong footholds in areas such as manufacturing, medical science, energy production, IT, sustainable resource development, and international culture and the arts, the city-state has created a vibrantly diverse center for innovation, analysts say.

"Singapore had no other choice," says Damien Duhamel, Solidiance managing director for Asia Pacific. "It had to adapt and change if it was to remain relevant in the 21st century."

Bruno Lanvin, executive director of INSEAD's European Competitiveness Initiative, agrees.

"Innovation has been the key to Singapore's success," he says, adding that Singapore has come a long way to become a city-state driven by technology.

Duhamel says although Singapore is still a young city and "things are not always perfect", it has built an attractive ecosystem for companies to innovate.

"The constantly evolving melting pot is not always easy to manage but creates real opportunities for those who are willing to grab them," he says.

In just a few decades it has evolved from being a labor-intensive manufacturing transhipment port to a high-tech production and world-class research and development center.

A report by the Massachusetts Biotechnology Council notes that Singapore is "aiming to move up the value chain and position itself as a world-class center for R&D through significant government investment".

Singapore's key strengths, the report says, are its educated and skilled workforce; a supportive government, business, [Company Incorporation USA]and regulatory environment; and government-supported research institutes.

The shift from low-cost labor-intensive manufacturing did not happen overnight. The transition has its roots in the 1970s when the island-state began to face competition from developing countries in the region.

The world was changing too, with the focus shifting to new, emerging technologies.